Electrochemotherapy in treatment of tumours

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Electrochemotherapy in treatment of tumours.

AIM Electrochemotherapy is a local drug delivery approach aimed at treatment with palliative intent of cutaneous and subcutaneous tumour nodules of different histologies. Electrochemotherapy, via cell membrane permeabilising electric pulses, potentiates the cytotoxicity of non-permeant or poorly permeant anticancer drugs with high intrinsic cytotoxicity, such as bleomycin or cisplatin, at the s...

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Electrochemotherapy in treatment of tumours

Electrochemotherapy is a combination therapy for cancer and consists of electroporation and treatment using cytostatic agents. Electroporation is a method that through an electric field temporarily opens the cell membrane which enhances the cytotoxic effect. Electrochemotherapy is used to a limited extent in Sweden and an essential question is if there is evidence that the method is effective a...

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Electrochemotherapy of tumours

Electrochemotherapy is a combined use of certain chemotherapeutic drugs and electric pulses applied to the treated tumour nodule. Local application of electric pulses to the tumour increases drug delivery into cells, specifically at the site of electric pulse application. Drug uptake by delivery of electric pulses is increased for only those chemotherapeutic drugs whose transport through the pl...

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Electrochemotherapy in Cancer Treatment

2. What is it? ............................................................................................................................ 3 2.

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Electrochemotherapy compared to surgery for treatment of canine mast cell tumours.

UNLABELLED The aim of this study was to evaluate the effectiveness of local treatment electrochemotherapy (ECT) with cisplatin and to compare it with effectiveness of surgery for treatment of mast cell tumours (MCT) in dogs. MATERIALS AND METHODS In the present retrospective study, 25 dogs of different breeds with MCT were divided into two treatment groups: surgery (16 dogs with 16 tumours) a...

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ژورنال

عنوان ژورنال: European Journal of Surgical Oncology (EJSO)

سال: 2008

ISSN: 0748-7983

DOI: 10.1016/j.ejso.2007.05.016